Diapedesis or extravasation. The meaning of DIAPEDESIS is the passage of blood cells through capillary walls into the tissues. . Medical dictionary definitions for diapedesis (cell function). e. The entire process of blood vessel escape is known as diapedesis. The entire process of blood vessel escape is known as diapedesis. diapedesis the passage of white blood cells through the unruptured wall of a blood vessel by changing in shape; an important reaction to tissue injury, leading to inflammation. , diapedesis) as they enter (intravasation) and exit (extravasation) the circulation. Jun 9, 2025 · Diapedesis, also known as transendothelial migration, is the process by which cells migrate through the endothelium, a layer of cells lining blood vessels and lymphatic vessels. Diapedesis is the process by which white blood cells (leukocytes) move through the walls of capillaries and enter the tissues to reach sites of infection or injury. Immune system functions require blood leukocytes to continuously traffic throughout the body and repeatedly cross endothelial barriers (i. Thus, trafficking of leukocytes requires their repeated crossing of endothelium (i. Once in the interstitial fluid, leukocytes migrate along a chemotactic gradient towards the site of injury or infection. Phonetic pronunciation, pictures, and related terms for Diapedesis. , diapedese) as they enter (intravasation) and exit (extravasation) the circulation. Leukocytes pass through spaces between blood vessel cells and the process from attachment to transport across the wall of the blood vessels is called diapedesis. Diapedesis is followed by movement of leukocytes toward the areas of infection marked by high concentration of inflammatory proteins. Jan 1, 2022 · This review will focus on recent advances in our understanding of mechanism of leukocyte crawling and diapedesis, with an emphasis on leukocyte–endothelial interactions and the signaling pathways they transduce to determine the mode of diapedesis, junctional or non-junctional. Diapedesis is the process by which blood cells, specifically leukocytes, pass through an intact vessel wall and migrate from the blood across blood vessel walls into tissue spaces as a consequence of constriction of endothelial cells in the wall. ddw4ezi5n1tzsinln4kf9ke3tf10g62jysb2uqk